Adamantyl-THPINACA

Adamantyl-THPINACA (ATHPINACA, AD-THPINACA)[1] is an indazole-based synthetic cannabinoid,[2] which was first reported to Europol in Slovenia in January 2015.[3] It is known as both the 1-adamantyl and 2-adamantyl isomers (SGT-40 and SGT-194 respectively), which can be distinguished by GC-EI-MS.[4] It is banned in Sweden[5] and Russia.[6] Both the 1-adamantyl and 2-adamantyl isomers are specifically listed as illegal drugs in Japan.[7] Given the known metabolic liberation (and presence as an impurity) of amantadine in the related compound APINACA, it is suspected that metabolic hydrolysis of the amide group of Adamantyl-THPINACA may also release amantadine.

Adamantyl-THPINACA
Legal status
Legal status
Identifiers
CAS Number
PubChem CID
UNII
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC24H31N3O2
Molar mass393.531 g·mol−1
3D model (JSmol)

See also

References
  1. "ATHPINACA isomer 1 (CAS 1400742-48-4)". Caymen Chemical. Retrieved 29 April 2017.
  2. "Muuntohuumeiden esiintyvyys 2015" (PDF). Finnish Medicines Agency. 7 May 2015. Retrieved 24 July 2015.
  3. Europol 2015 Annual Report on the implementation of Council Decision 2005/387/JHA
  4. Asada A, Doi T, Tagami T, Takeda A, Sawabe Y (March 2017). "Isomeric discrimination of synthetic cannabinoids by GC-EI-MS: 1-adamantyl and 2-adamantyl isomers of N-adamantyl carboxamides". Drug Testing and Analysis. 9 (3): 378–388. doi:10.1002/dta.2124. PMID 27770510.
  5. "Fler ämnen föreslås bli klassade som narkotika eller hälsofarlig vara". Folkhälsomyndigheten. Retrieved 24 July 2015.
  6. List of substances prohibited in the Russian Federation
  7. 指定薬物一覧
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