Cannabinodiol

Cannabinodiol
Clinical data
ATC code	None;
Legal status
Legal status	CA: Schedule II ; UK: Under Psychoactive Substances Act ;
Identifiers
	IUPAC name 5'-Methyl-4-pentyl-2'-(prop-1-en-2-yl)-[1,1'-biphenyl]-2,6-diol;
CAS Number	39624-81-2;
PubChem CID	11551346;
ChemSpider	9726124;
Chemical and physical data
Formula	C21H26O2
Molar mass	310.437 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CCCCCC1=CC(=C(C(=C1)O)C2=C(C=CC(=C2)C)C(=C)C)O;
	InChI InChI=1S/C21H26O2/c1-5-6-7-8-16-12-19(22)21(20(23)13-16)18-11-15(4)9-10-17(18)14(2)3/h9-13,22-23H,2,5-8H2,1,3-4H3; Key:TWKHUZXSTKISQC-UHFFFAOYSA-N;

Cannabinodiol (also known as cannabidinodiol and CBND)[1] is a psychoactive[2] cannabinoid that is present in the plant Cannabis sativa at low concentrations.[3] It is the fully aromatized derivative of cannabidiol (CBD) and can occur as a product of the photochemical conversion of cannabinol (CBN).[4]

References

US 9084771, McAllister SD, Desprez PY, "Methods and compositions for treating cancer", published 21 July 2015, assigned to Sutter West Bay Hospitals
Lewis MM, Yang Y, Wasilewski E, Clarke HA, Kotra LP (September 2017). "Chemical Profiling of Medical Cannabis Extracts". ACS Omega. 2 (9): 6091–6103. doi:10.1021/acsomega.7b00996. PMC 6044620. PMID 30023762. Δ9-THC, cannabinol (CBN), and cannabinodiol (CBND) are known to be psychoactive
Robert JJCh L, Ludwig Bercht CA, van Ooyen R, Spronck HJ (1 January 1977). "Cannabinodiol: Conclusive identification and synthesis of a new cannabinoid from Cannabis sativa". Phytochemistry. 16 (5): 595–597. doi:10.1016/0031-9422(77)80023-X.
Elsohly MA, Slade D (December 2005). "Chemical constituents of marijuana: the complex mixture of natural cannabinoids". Life Sciences. Natureceuticals (Natural Products), Nutraceuticals, Herbal Botanicals, and Psychoactives: Drug Discovery and Drug-Drug Interactions; Volume I: Natureceuticals (Natural Products), Herbal Botanicals, Psychoactive Hallucinogens and Related Products. 78 (5): 539–48. doi:10.1016/j.lfs.2005.09.011. PMID 16199061.

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[1] US 9084771, McAllister SD, Desprez PY, "Methods and compositions for treating cancer", published 21 July 2015, assigned to Sutter West Bay Hospitals

[2] Lewis MM, Yang Y, Wasilewski E, Clarke HA, Kotra LP (September 2017). "Chemical Profiling of Medical Cannabis Extracts". ACS Omega. 2 (9): 6091–6103. doi:10.1021/acsomega.7b00996. PMC 6044620. PMID 30023762. Δ9-THC, cannabinol (CBN), and cannabinodiol (CBND) are known to be psychoactive

[3] Robert JJCh L, Ludwig Bercht CA, van Ooyen R, Spronck HJ (1 January 1977). "Cannabinodiol: Conclusive identification and synthesis of a new cannabinoid from Cannabis sativa". Phytochemistry. 16 (5): 595–597. doi:10.1016/0031-9422(77)80023-X.

[4] Elsohly MA, Slade D (December 2005). "Chemical constituents of marijuana: the complex mixture of natural cannabinoids". Life Sciences. Natureceuticals (Natural Products), Nutraceuticals, Herbal Botanicals, and Psychoactives: Drug Discovery and Drug-Drug Interactions; Volume I: Natureceuticals (Natural Products), Herbal Botanicals, Psychoactive Hallucinogens and Related Products. 78 (5): 539–48. doi:10.1016/j.lfs.2005.09.011. PMID 16199061.

Cannabinodiol

See also

References