Copper(II) chloride

Copper(II) chloride is the chemical compound with the chemical formula CuCl2. This is a light brown solid, which slowly absorbs moisture to form a blue-green dihydrate.

Copper(II) chloride

Anhydrous

Anhydrous

Dihydrate
Names
Other names
Cupric chloride
Identifiers
3D model (JSmol)
8128168
ChEBI
ChEMBL
ChemSpider
DrugBank
ECHA InfoCard 100.028.373
EC Number
  • 231-210-2
9300
RTECS number
  • GL7000000
UNII
UN number 2802
Properties
CuCl2
Molar mass 134.45 g/mol (anhydrous)
170.48 g/mol (dihydrate)
Appearance yellow-brown solid (anhydrous)
blue-green solid (dihydrate)
Odor odorless
Density 3.386 g/cm3 (anhydrous)
2.51 g/cm3 (dihydrate)
Melting point 498 °C (928 °F; 771 K) (anhydrous)
100 °C (dehydration of dihydrate)
Boiling point 993 °C (1,819 °F; 1,266 K) (anhydrous, decomposes)
70.6 g/100 mL (0 °C)
75.7 g/100 mL (25 °C)
107.9 g/100 mL (100 °C)
Solubility methanol:
68 g/100 mL (15 °C)


ethanol:
53 g/100 mL (15 °C)
soluble in acetone

+1080·10−6 cm3/mol
Structure
distorted CdI2 structure
Octahedral
Hazards
Safety data sheet Fisher Scientific
GHS pictograms
GHS Signal word Danger
H301, H302, H312, H315, H318, H319, H335, H400, H410, H411
P261, P264, P270, P271, P273, P280, P301+310, P301+312, P302+352, P304+340, P305+351+338, P310, P312, P321, P322, P330, P332+313, P337+313, P362, P363, P391, P403+233, P405, P501
NFPA 704 (fire diamond)
Flammability code 0: Will not burn. E.g. waterHealth code 2: Intense or continued but not chronic exposure could cause temporary incapacitation or possible residual injury. E.g. chloroformReactivity code 1: Normally stable, but can become unstable at elevated temperatures and pressures. E.g. calciumSpecial hazards (white): no code
0
2
1
Flash point Non-flammable
NIOSH (US health exposure limits):
PEL (Permissible)
 TWA 1 mg/m3 (as Cu)[1]
REL (Recommended)
 TWA 1 mg/m3 (as Cu)[1]
IDLH (Immediate danger)
 TWA 100 mg/m3 (as Cu)[1]
Related compounds
Other anions
 Copper(II) fluoride
Copper(II) bromide
Other cations
 Copper(I) chloride
Silver chloride
Gold(III) chloride
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is YN ?)
Infobox references

Both the anhydrous and the dihydrate forms occur naturally as the very rare minerals tolbachite and eriochalcite, respectively.[2]

Structure

Anhydrous CuCl2 adopts a distorted cadmium iodide structure. In this motif, the copper centers are octahedral. Most copper(II) compounds exhibit distortions from idealized octahedral geometry due to the Jahn-Teller effect, which in this case describes the localization of one d-electron into a molecular orbital that is strongly antibonding with respect to a pair of chloride ligands. In CuCl2·2H2O, the copper again adopts a highly distorted octahedral geometry, the Cu(II) centers being surrounded by two water ligands and four chloride ligands, which bridge asymmetrically to other Cu centers.[3]

Copper(II) chloride is paramagnetic. Of historical interest, CuCl2·2H2O was used in the first electron paramagnetic resonance measurements by Yevgeny Zavoisky in 1944.[4][5]

Properties and reactions
Aqueous solutions of copper(II) chloride. Greenish when high in [Cl−], more blue when lower in [Cl−].

Aqueous solution prepared from copper(II) chloride contain a range of copper(II) complexes depending on concentration, temperature, and the presence of additional chloride ions. These species include blue color of [Cu(H2O)6]2+ and yellow or red color of the halide complexes of the formula [CuCl2+x]x−.[6]

Hydrolysis

Copper(II) hydroxide precipitates upon treating copper(II) chloride solutions with base:

CuCl2 + 2 NaOH → Cu(OH)2 + 2 NaCl
Copper(II) chloride dihydrate crystal

Partial hydrolysis gives dicopper chloride trihydroxide, Cu2(OH)3Cl, a popular fungicide.

Redox

Copper(II) chloride is a mild oxidant. It decomposes to copper(I) chloride and chlorine gas near 1000 °C:

2 CuCl2 → 2 CuCl + Cl2

Copper(II) chloride (CuCl2) reacts with several metals to produce copper metal or copper(I) chloride (CuCl) with oxidation of the other metal. To convert copper(II) chloride to copper(I) chloride, it can be convenient to reduce an aqueous solution with sulfur dioxide as the reductant:

2 CuCl2 + SO2 + 2 H2O → 2 CuCl + 2 HCl + H2SO4

Coordination complexes

CuCl2 reacts with HCl or other chloride sources to form complex ions: the red CuCl3− (it is a dimer in reality, Cu2Cl62−, a couple of tetrahedrons that share an edge), and the green or yellow CuCl42−.[7]

CuCl
2 + Cl−
 ⇌ CuCl−
3
CuCl
2 + 2 Cl−
 ⇌ CuCl2−
4

Some of these complexes can be crystallized from aqueous solution, and they adopt a wide variety of structures.

Copper(II) chloride also forms a variety of coordination complexes with ligands such as ammonia, pyridine and triphenylphosphine oxide:

CuCl2 + 2 C5H5N → [CuCl2(C5H5N)2] (tetragonal)
CuCl2 + 2 (C6H5)3PO → [CuCl2((C6H5)3PO)2] (tetrahedral)

However "soft" ligands such as phosphines (e.g., triphenylphosphine), iodide, and cyanide as well as some tertiary amines induce reduction to give copper(I) complexes.

Preparation

Copper(II) chloride is prepared commercially by the action of chlorination of copper. Copper at red heat (300-400°C) combines directly with chlorine gas, giving (molten) copper (II) chloride. The reaction is very exothermic.

Cu(s) + Cl2(g) → CuCl2(l)

It is also commercially practical to combine copper(II) oxide with an excess of ammonium chloride at similar temperatures, producing copper chloride, ammonia, and water:

CuO + 2NH4Cl → CuCl2 + 2NH3 + H2O

Although copper metal itself cannot be oxidised by hydrochloric acid, copper-containing bases such as the hydroxide, oxide, or copper(II) carbonate can react to form CuCl2 in an acid-base reaction.

Once prepared, a solution of CuCl2 may be purified by crystallization. A standard method takes the solution mixed in hot dilute hydrochloric acid, and causes the crystals to form by cooling in a Calcium chloride (CaCl2)-ice bath.[8][9]

There are indirect and rarely used means of using copper ions in solution to form copper(II) chloride. Electrolysis of aqueous sodium chloride with copper electrodes produces (among other things) a blue-green foam that can be collected and converted to the hydrate. While this is not usually done due to the emission of toxic chlorine gas, and the prevalence of the more general chloralkali process, the electrolysis will convert the copper metal to copper ions in solution forming the compound. Indeed, any solution of copper ions can be mixed with hydrochloric acid and made into a copper chloride by removing any other ions.

Natural occurrence

Copper(II) chloride occurs naturally as the very rare anhydrous mineral tolbachite and the dihydrate eriochalcite.[2] Both are found near fumaroles and in some Cu mines.[10][11][12] More common are mixed oxyhydroxide-chlorides like atacamite Cu2(OH)3Cl, arising among Cu ore beds oxidation zones in arid climate (also known from some altered slags).

Uses

Co-catalyst in Wacker process

A major industrial application for copper(II) chloride is as a co-catalyst with palladium(II) chloride in the Wacker process. In this process, ethene (ethylene) is converted to ethanal (acetaldehyde) using water and air. During the reaction, PdCl2 is reduced to Pd, and the CuCl2 serves to re-oxidize this back to PdCl2. Air can then oxidize the resultant CuCl back to CuCl2, completing the cycle.

  1. C2H4 + PdCl2 + H2O → CH3CHO + Pd + 2 HCl
  2. Pd + 2 CuCl2 → 2 CuCl + PdCl2
  3. 4 CuCl + 4 HCl + O2 → 4 CuCl2 + 2 H2O

The overall process is:

2 C2H4 + O2 → 2 CH3CHO

Catalyst in production of chlorine

Copper(II) chloride is used as a catalyst in a variety of processes that produce chlorine by oxychlorination. The Deacon process takes place at about 400 to 450 °C in the presence of a copper chloride:

4 HCl + O2 → 2 Cl2 + 2 H2O

Copper(II) chloride catalyzes the chlorination in the production of vinyl chloride and dichloroethane.[13]

Copper(II) chloride is used in the Copper–chlorine cycle in which it splits steam into a copper oxygen compound and hydrogen chloride, and is later recovered in the cycle from the electrolysis of copper(I) chloride.

Other organic synthetic applications

Copper(II) chloride has some highly specialized applications in the synthesis of organic compounds.[8] It effects chlorination of aromatic hydrocarbons- this is often performed in the presence of aluminium oxide. It is able to chlorinate the alpha position of carbonyl compounds:[14]

This reaction is performed in a polar solvent such as dimethylformamide (DMF), often in the presence of lithium chloride, which accelerates the reaction.

CuCl2, in the presence of oxygen, can also oxidize phenols. The major product can be directed to give either a quinone or a coupled product from oxidative dimerization. The latter process provides a high-yield route to 1,1-binaphthol:[15]

Such compounds are intermediates in the synthesis of BINAP and its derivatives

Copper(II) chloride dihydrate promotes the hydrolysis of acetonides, i.e., for deprotection to regenerate diols[16] or aminoalcohols, as in this example (where TBDPS = tert-butyldiphenylsilyl):[17]

CuCl2 also catalyses the free radical addition of sulfonyl chlorides to alkenes; the alpha-chlorosulfone may then undergo elimination with base to give a vinyl sulfone product.

Niche uses

Copper(II) chloride is also used in pyrotechnics as a blue/green coloring agent. In a flame test, copper chlorides, like all copper compounds, emit green-blue.

In humidity indicator cards (HICs), cobalt-free brown to azure (copper(II) chloride base) HICs can be found on the market. In 1998, the European Community (EC) classified items containing cobalt(II) chloride of 0.01 to 1% w/w as T (Toxic), with the corresponding R phrase of R49 (may cause cancer if inhaled). As a consequence, new cobalt-free humidity indicator cards have been developed that contain copper.

Safety

Copper(II) chloride can be toxic. Only concentrations below 5 ppm are allowed in drinking water by the US Environmental Protection Agency.

References
  1. NIOSH Pocket Guide to Chemical Hazards. "#0150". National Institute for Occupational Safety and Health (NIOSH).
  2. Marlene C. Morris, Howard F. McMurdie, Eloise H. Evans, Boris Paretzkin, Harry S. Parker, and Nicolas C. Panagiotopoulos (1981) Copper chloride hydrate (eriochalcite), in Standard X-ray Diffraction Powder Patterns National Bureau of Standards, Monograph 25, Section 18; page 33.
  3. Wells, A.F. (1984) Structural Inorganic Chemistry, Oxford: Clarendon Press. ISBN 0-19-855370-6.
  4. Peter Baláž (2008). Mechanochemistry in Nanoscience and Minerals Engineering. Springer. p. 167. ISBN 978-3-540-74854-0.
  5. Marina Brustolon (2009). Electron paramagnetic resonance: a practitioner's toolkit. John Wiley and Sons. p. 3. ISBN 978-0-470-25882-8.
  6. Greenwood, N. N. and Earnshaw, A. (1997). Chemistry of the Elements (2nd Edn.), Oxford:Butterworth-Heinemann. ISBN 0-7506-3365-4.
  7. Naida S. Gill; F. B. Taylor (1967). Tetrahalo Complexes of Dipositive Metals in the First Transition Series. Inorganic Syntheses. 9. pp. 136–142. doi:10.1002/9780470132401.ch37. ISBN 978-0-470-13240-1.
  8. S. H. Bertz, E. H. Fairchild, in Handbook of Reagents for Organic Synthesis, Volume 1: Reagents, Auxiliaries and Catalysts for C-C Bond Formation, (R. M. Coates, S. E. Denmark, eds.), pp. 220-3, Wiley, New York, 1738.
  9. W. L. F. Armarego; Christina Li Lin Chai (2009-05-22). Purification of Laboratory Chemicals (Google Books excerpt) (6th ed.). Butterworth-Heinemann. p. 461. ISBN 978-1-85617-567-8.
  10. https://www.mindat.org/min-3990.html
  11. https://www.mindat.org/min-1398.html
  12. https://www.ima-mineralogy.org/Minlist.htm
  13. H.Wayne Richardson, "Copper Compounds" in Ullmann's Encyclopedia of Industrial Chemistry, 2005, Wiley-VCH, Weinheim, doi:10.1002/14356007.a07_567
  14. C. E. Castro; E. J. Gaughan; D. C. Owsley (1965). "Cupric Halide Halogenations". Journal of Organic Chemistry. 30 (2): 587. doi:10.1021/jo01013a069.
  15. J. Brussee; J. L. G. Groenendijk; J. M. Koppele; A. C. A. Jansen (1985). "On the mechanism of the formation of s(−)-(1, 1'-binaphthalene)-2,2'-diol via copper(II)amine complexes". Tetrahedron. 41 (16): 3313. doi:10.1016/S0040-4020(01)96682-7.
  16. Chandrasekhar, M.; Kusum L. Chandra; Vinod K. Singh (2003). "Total Synthesis of (+)-Boronolide, (+)-Deacetylboronolide, and (+)-Dideacetylboronolide". Journal of Organic Chemistry. 68 (10): 4039–4045. doi:10.1021/jo0269058. PMID 12737588.
  17. Krishna, Palakodety Radha; G. Dayaker (2007). "A stereoselective total synthesis of (−)-andrachcinidine via an olefin cross-metathesis protocol". Tetrahedron Letters. Elsevier. 48 (41): 7279–7282. doi:10.1016/j.tetlet.2007.08.053.

Further reading
  1. Greenwood, Norman N.; Earnshaw, Alan (1997). Chemistry of the Elements (2nd ed.). Butterworth-Heinemann. ISBN 978-0-08-037941-8.
  2. Lide, David R. (1990). CRC handbook of chemistry and physics: a ready-reference book of chemical and physical data. Boca Raton: CRC Press. ISBN 0-8493-0471-7.
  3. The Merck Index, 7th edition, Merck & Co, Rahway, New Jersey, USA, 1960.
  4. D. Nicholls, Complexes and First-Row Transition Elements, Macmillan Press, London, 1973.
  5. A. F. Wells, 'Structural Inorganic Chemistry, 5th ed., Oxford University Press, Oxford, UK, 1984.
  6. J. March, Advanced Organic Chemistry, 4th ed., p. 723, Wiley, New York, 1992.
  7. Fieser & Fieser Reagents for Organic Synthesis Volume 5, p158, Wiley, New York, 1975.
  8. D. W. Smith (1976). "Chlorocuprates(II)". Coordination Chemistry Reviews. 21 (2–3): 93–158. doi:10.1016/S0010-8545(00)80445-2.
Salts and covalent derivatives of the chloride ion
HCl He
LiCl BeCl2 BCl3
B2Cl4		 CCl4 NCl3
ClN3		 Cl2O
ClO2
Cl2O7		 ClF
ClF3
ClF5		 Ne
NaCl MgCl2 AlCl
AlCl3		 SiCl4 P2Cl4
PCl3
PCl5		 S2Cl2
SCl2
SCl4		 Cl2 Ar
KCl CaCl
CaCl2		 ScCl3 TiCl2
TiCl3
TiCl4		 VCl2
VCl3
VCl4
VCl5		 CrCl2
CrCl3
CrCl4		 MnCl2 FeCl2
FeCl3		 CoCl2
CoCl3		 NiCl2 CuCl
CuCl2		 ZnCl2 GaCl2
GaCl3		 GeCl2
GeCl4		 AsCl3
AsCl5		 Se2Cl2
SeCl4		 BrCl KrCl
RbCl SrCl2 YCl3 ZrCl3
ZrCl4		 NbCl3
NbCl4
NbCl5		 MoCl2
MoCl3
MoCl4
MoCl5
MoCl6		 TcCl3
TcCl4		 RuCl3 RhCl3 PdCl2 AgCl CdCl2 InCl
InCl2
InCl3		 SnCl2
SnCl4		 SbCl3
SbCl5		 Te3Cl2
TeCl4		 ICl
ICl3		 XeCl
XeCl2
XeCl4
CsCl BaCl2   HfCl4 TaCl5 WCl2
WCl3
WCl4
WCl5
WCl6		 Re3Cl9
ReCl4
ReCl5
ReCl6		 OsCl4 IrCl2
IrCl3
IrCl4		 PtCl2
PtCl4		 AuCl
AuCl3		 Hg2Cl2,
HgCl2		 TlCl PbCl2,
PbCl4		 BiCl3 PoCl2,
PoCl4		 AtCl RnCl2
FrCl RaCl2   RfCl4 Db Sg Bh Hs Mt Ds Rg Cn Nh Fl Mc Lv Ts Og
↓
LaCl3 CeCl3 PrCl3 NdCl2,
NdCl3		 PmCl3 SmCl2,
SmCl3		 EuCl2,
EuCl3		 GdCl3 TbCl3 DyCl2,
DyCl3		 HoCl3 ErCl3 TmCl2
TmCl3		 YbCl2
YbCl3		 LuCl3
AcCl3 ThCl4 PaCl5 UCl3
UCl4
UCl5
UCl6		 NpCl4 PuCl3 AmCl2
AmCl3		 CmCl3 BkCl3 CfCl3 EsCl3 Fm Md No LrCl3
This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.