EIF3F

Eukaryotic translation initiation factor 3 subunit F (eIF3f) is a protein that in humans is encoded by the EIF3F gene.[4][5]

EIF3F
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesEIF3F, EIF3S5, eIF3-p47, eukaryotic translation initiation factor 3 subunit F, MRT67
External IDsOMIM: 603914 MGI: 1913335 HomoloGene: 2783 GeneCards: EIF3F
EC number3.4.19.12
Gene location (Human)
Chr.Chromosome 11 (human)[1]
Band11p15.4Start7,970,251 bp[1]
End8,001,862 bp[1]
Orthologs
SpeciesHumanMouse
Entrez

8665

66085

Ensembl

ENSG00000175390

ENSMUSG00000031029

UniProt

O00303

Q9DCH4

RefSeq (mRNA)

NM_003754

NM_025344

RefSeq (protein)

NP_003745

NP_079620

Location (UCSC)Chr 11: 7.97 – 8 Mbn/a
PubMed search[2][3]
Wikidata
View/Edit HumanView/Edit Mouse

Interactions

EIF3F has been shown to interact with Mammalian target of rapamycin[6] and EIF3A.[7][8][9]

See also

References

  1. GRCh38: Ensembl release 89: ENSG00000175390 - Ensembl, May 2017
  2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. Asano K, Vornlocher HP, Richter-Cook NJ, Merrick WC, Hinnebusch AG, Hershey JW (Nov 1997). "Structure of cDNAs encoding human eukaryotic initiation factor 3 subunits. Possible roles in RNA binding and macromolecular assembly". J. Biol. Chem. 272 (43): 27042–52. doi:10.1074/jbc.272.43.27042. PMID 9341143.
  5. "Entrez Gene: EIF3S5 eukaryotic translation initiation factor 3, subunit 5 epsilon, 47kDa".
  6. Harris TE, Chi A, Shabanowitz J, Hunt DF, Rhoads RE, Lawrence JC (Apr 2006). "mTOR-dependent stimulation of the association of eIF4G and eIF3 by insulin". EMBO J. 25 (8): 1659–68. doi:10.1038/sj.emboj.7601047. PMC 1440840. PMID 16541103.
  7. Ewing RM, Chu P, Elisma F, Li H, Taylor P, Climie S, McBroom-Cerajewski L, Robinson MD, O'Connor L, Li M, Taylor R, Dharsee M, Ho Y, Heilbut A, Moore L, Zhang S, Ornatsky O, Bukhman YV, Ethier M, Sheng Y, Vasilescu J, Abu-Farha M, Lambert JP, Duewel HS, Stewart II, Kuehl B, Hogue K, Colwill K, Gladwish K, Muskat B, Kinach R, Adams SL, Moran MF, Morin GB, Topaloglou T, Figeys D (2007). "Large-scale mapping of human protein–protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931.
  8. Mayeur GL, Fraser CS, Peiretti F, Block KL, Hershey JW (Oct 2003). "Characterization of eIF3k: a newly discovered subunit of mammalian translation initiation factor elF3". Eur. J. Biochem. 270 (20): 4133–9. doi:10.1046/j.1432-1033.2003.03807.x. PMID 14519125.
  9. Block KL, Vornlocher HP, Hershey JW (Nov 1998). "Characterization of cDNAs encoding the p44 and p35 subunits of human translation initiation factor eIF3". J. Biol. Chem. 273 (48): 31901–8. doi:10.1074/jbc.273.48.31901. PMID 9822659.

Further reading


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