EIF3S6

Eukaryotic translation initiation factor 3 subunit E (eIF3e) is a protein that in humans is encoded by the EIF3E gene.[5][6][7]

EIF3E
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesEIF3E, EIF3-P48, EIF3S6, INT6, eIF3-p46, eukaryotic translation initiation factor 3 subunit E
External IDsOMIM: 602210 MGI: 99257 HomoloGene: 1205 GeneCards: EIF3E
Gene location (Human)
Chr.Chromosome 8 (human)[1]
Band8q23.1Start108,201,216 bp[1]
End108,435,333 bp[1]
RNA expression pattern
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

3646

16341

Ensembl

ENSG00000104408

ENSMUSG00000022336

UniProt

P60228

P60229

RefSeq (mRNA)

NM_001568

NM_008388

RefSeq (protein)

NP_001559

NP_032414

Location (UCSC)Chr 8: 108.2 – 108.44 MbChr 15: 43.25 – 43.28 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Interactions

EIF3S6 has been shown to interact with:

See also

References

  1. GRCh38: Ensembl release 89: ENSG00000104408 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000022336 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Miyazaki S, Imatani A, Ballard L, Marchetti A, Buttitta F, Albertsen H, Nevanlinna HA, Gallahan D, Callahan R (1997). "The chromosome location of the human homolog of the mouse mammary tumor-associated gene INT6 and its status in human breast carcinomas". Genomics. 46 (1): 155–8. doi:10.1006/geno.1997.4996. PMID 9403073.
  6. Asano K, Merrick WC, Hershey JW (October 1997). "The translation initiation factor eIF3-p48 subunit is encoded by int-6, a site of frequent integration by the mouse mammary tumor virus genome". J. Biol. Chem. 272 (38): 23477–80. doi:10.1074/jbc.272.38.23477. PMID 9295280.
  7. "Entrez Gene: EIF3S6 Eukaryotic translation initiation factor 3, subunit 6 48kDa".
  8. Lehner B, Semple JI, Brown SE, Counsell D, Campbell RD, Sanderson CM (January 2004). "Analysis of a high-throughput yeast two-hybrid system and its use to predict the function of intracellular proteins encoded within the human MHC class III region". Genomics. 83 (1): 153–67. doi:10.1016/s0888-7543(03)00235-0. PMID 14667819.
  9. Hoareau Alves K, Bochard V, Réty S, Jalinot P (September 2002). "Association of the mammalian proto-oncoprotein Int-6 with the three protein complexes eIF3, COP9 signalosome and 26S proteasome". FEBS Lett. 527 (1–3): 15–21. doi:10.1016/s0014-5793(02)03147-2. PMID 12220626. S2CID 39308598.
  10. Ewing RM, Chu P, Elisma F, Li H, Taylor P, Climie S, McBroom-Cerajewski L, Robinson MD, O'Connor L, Li M, Taylor R, Dharsee M, Ho Y, Heilbut A, Moore L, Zhang S, Ornatsky O, Bukhman YV, Ethier M, Sheng Y, Vasilescu J, Abu-Farha M, Lambert JP, Duewel HS, Stewart II, Kuehl B, Hogue K, Colwill K, Gladwish K, Muskat B, Kinach R, Adams SL, Moran MF, Morin GB, Topaloglou T, Figeys D (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Mol. Syst. Biol. 3: 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931.
  11. Mayeur GL, Fraser CS, Peiretti F, Block KL, Hershey JW (October 2003). "Characterization of eIF3k: a newly discovered subunit of mammalian translation initiation factor elF3". Eur. J. Biochem. 270 (20): 4133–9. doi:10.1046/j.1432-1033.2003.03807.x. PMID 14519125.
  12. Morris-Desbois C, Réty S, Ferro M, Garin J, Jalinot P (December 2001). "The human protein HSPC021 interacts with Int-6 and is associated with eukaryotic translation initiation factor 3". J. Biol. Chem. 276 (49): 45988–95. doi:10.1074/jbc.M104966200. PMID 11590142.
  13. Morris-Desbois C, Bochard V, Reynaud C, Jalinot P (October 1999). "Interaction between the Ret finger protein and the Int-6 gene product and co-localisation into nuclear bodies". J. Cell Sci. 112 ( Pt 19): 3331–42. PMID 10504338.

Further reading


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