Glia maturation factor
Glia maturation factor is a neurotrophic factor implicated in nervous system development, angiogenesis and immune function. In humans, the glia maturation factor beta and glia maturation factor gamma proteins are encoded by the GMFB and GMFG genes, respectively.
| glia maturation factor, beta | |||||||
|---|---|---|---|---|---|---|---|
| Identifiers | |||||||
| Symbol | GMFB | ||||||
| NCBI gene | 2764 | ||||||
| HGNC | 4373 | ||||||
| OMIM | 601713 | ||||||
| RefSeq | NM_004124 | ||||||
| UniProt | P60983 | ||||||
| Other data | |||||||
| Locus | Chr. 14 q22.1 | ||||||
| |||||||
| glia maturation factor, gamma | |||||||
|---|---|---|---|---|---|---|---|
| Identifiers | |||||||
| Symbol | GMFG | ||||||
| NCBI gene | 9535 | ||||||
| HGNC | 4374 | ||||||
| OMIM | 604104 | ||||||
| RefSeq | NM_004877 | ||||||
| UniProt | O60234 | ||||||
| Other data | |||||||
| Locus | Chr. 19 q13.2 | ||||||
| |||||||
The structures of mouse glia maturation factors beta and gamma, solved by both crystallography and NMR, reveal similarities and critical differences with ADF-H (actin depolymerization factor homology) domains and suggest new means of experimentally addressing the function of this protein family.[1]
References
- "Protein Summary". Retrieved 2008-10-31.
See also
Stereo ribbon diagram of the crystal structure of GMFG. Spectral coloring is from blue (N-terminus) to red (C-terminus). Secondary structural elements are indicated
- Glia+maturation+factor at the US National Library of Medicine Medical Subject Headings (MeSH)
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