JWH-047
JWH-047 is a selective cannabinoid ligand that binds to both CB1 and CB2. It has a bindining affinity of Ki = 0.9 nM for the CB2 subtype, and more than 65 times selectivity over the CB1.[1]
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| Formula | C25H25NO |
| Molar mass | 355.481 g·mol−1 |
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In the United States, all CB1 receptor agonists of the 3-(1-naphthoyl)indole class such as JWH-047 are Schedule I Controlled Substances.[2]
References
- Aung MM, Griffin G, Huffman JW, Wu MJ, Keel C, Yang B, Showalter VM, Abood ME, Martin BR (2000). "Influence of the N-1 alkyl chain length of cannabimimetic indoles upon CB1 and CB2 receptor binding". Drug and Alcohol Dependence. 60 (2): 133–40. doi:10.1016/S0376-8716(99)00152-0. PMID 10940540.
- : Schedules of controlled substances
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