Niludipine

Niludipine
Names
	Preferred IUPAC name Bis(2-propoxyethyl) 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
	Other names 2,6-Dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid bis(2-propoxyethyl) ester
Identifiers
CAS Number	22609-73-0 ;
3D model (JSmol)	Interactive image;
ChemSpider	81025;
ECHA InfoCard	100.041.003
EC Number	245-120-6;
MeSH	C019497
PubChem CID	89767;
UNII	9844OS3B0J ;
CompTox Dashboard (EPA)	DTXSID20945267 ;
	InChI InChI=1S/C25H34N2O8/c1-5-10-32-12-14-34-24(28)21-17(3)26-18(4)22(25(29)35-15-13-33-11-6-2)23(21)19-8-7-9-20(16-19)27(30)31/h7-9,16,23,26H,5-6,10-15H2,1-4H3 Key: VZWXXKDFACOXNT-UHFFFAOYSA-N; InChI=1/C25H34N2O8/c1-5-10-32-12-14-34-24(28)21-17(3)26-18(4)22(25(29)35-15-13-33-11-6-2)23(21)19-8-7-9-20(16-19)27(30)31/h7-9,16,23,26H,5-6,10-15H2,1-4H3 Key: VZWXXKDFACOXNT-UHFFFAOYAS;
	SMILES CCCOCCOC(=O)C1=C(NC(=C(C1C2=CC(=CC=C2)[N+](=O)[O-])C(=O)OCCOCCC)C)C;
Properties
Chemical formula	C25H34N2O8
Molar mass	490.553 g·mol−1
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
	verify (what is ?)
	Infobox references

Niludipine is a calcium channel blocker of the dihydropyridine class. It is a vasodilator that acts upon the coronary arteries of the heart-lung. It was found to produce a calcium antagonistic effect on the smooth muscle of hearts of canines and guinea pigs inhibiting myocardial oxidative metabolism.[1]

References

Hashimoto, K (1979). "Effects of niludipine on the Cardiovascular system with a note on its Calcium-Antagonistic effects". Arzneimittel-Forschung. 29 (9): 1368–73. PMID 583243.

This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.

[1] Hashimoto, K (1979). "Effects of niludipine on the Cardiovascular system with a note on its Calcium-Antagonistic effects". Arzneimittel-Forschung. 29 (9): 1368–73. PMID 583243.