Valproate pivoxil

Valproate pivoxil
Clinical data
Routes of; administration	Oral
ATC code	none;
Legal status
Legal status	In general: ℞ (Prescription only);
Identifiers
	IUPAC name [(2,2-dimethylpropanoyl)oxy]methyl 2-propylpentanoate;
CAS Number	77372-61-3 ;
PubChem CID	71160;
ChemSpider	64301 ;
UNII	9F5A05A29T;
CompTox Dashboard (EPA)	DTXSID40228089 ;
ECHA InfoCard	100.071.502
Chemical and physical data
Formula	C14H26O4
Molar mass	258.358 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES O=C(OCOC(=O)C(C)(C)C)C(CCC)CCC;
	InChI InChI=1S/C14H26O4/c1-6-8-11(9-7-2)12(15)17-10-18-13(16)14(3,4)5/h11H,6-10H2,1-5H3 ; Key:DJEFRLDEQKSNLM-UHFFFAOYSA-N ;
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Valproate pivoxil (Pivadin, Valproxen) is an anticonvulsant used in the treatment of epilepsy.[1] It is the pivaloyloxymethyl ester derivative of valproic acid.[2] It is likely a prodrug of valproic acid, as pivoxil esters are commonly employed to make prodrugs in medicinal chemistry.

References

Triggle DJ (1997). Dictionary of pharmacological agents. London: Chapman & Hall. ISBN 0-412-46630-9.
Hall JA, Morton IK (1999). Concise dictionary of pharmacological agents: properties and synonyms. Kluwer Academic. p. 342. ISBN 0-7514-0499-3.

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Mood stabilizers
Anticonvulsants	Carbamazepine Lamotrigine Oxcarbazepine Valproate Valnoctamide Valproate pivoxil Valpromide
Atypical antipsychotics	Aripiprazole Cariprazine Clozapine Lurasidone Olanzapine (+fluoxetine) Paliperidone Quetiapine Risperidone Ziprasidone
Others	Ketamine Lithium (lithium acetate, lithium carbonate, lithium chloride, lithium citrate, lithium hydroxide, lithium orotate) Omega-3 fatty acids (docosahexaenoic acid, eicosapentaenoic acid)