Acetohexamide
Acetohexamide (trade name Dymelor) is a first-generation sulfonylurea medication used to treat diabetes mellitus type 2, particularly in people whose diabetes cannot be controlled by diet alone.
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| Trade names | Dymelor |
| AHFS/Drugs.com | Micromedex Detailed Consumer Information |
| MedlinePlus | a602021 |
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| Protein binding | 90% |
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| ECHA InfoCard | 100.012.301  |
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| Formula | C15H20N2O4S |
| Molar mass | 324.40 g·mol−1 |
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| Melting point | 188 to 190 °C (370 to 374 °F) |
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Mechanism of action
Acetohexamide lowers blood sugar by stimulating the pancreas to secrete insulin and helping the body use insulin efficiently.[1] The pancreas must produce insulin for this medication to work. For this reason, acetohexamide is not used to treat diabetes mellitus type 1.
Risks
Oral hypoglycemic drugs, including acetohexamide, have been associated with increased cardiovascular mortality. Talk to your doctor about the possible risks, benefits, and alternatives of using this drug for your condition.[2]
References
- "Archived copy". Archived from the original on 2011-11-05. Retrieved 2011-10-26.CS1 maint: archived copy as title (link) – Metformin Side Effects
- Medline Plus Archived September 11, 2005, at the Wayback Machine – Acetohexamide
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