Fluocortin butyl

Fluocortin butyl (brand names Lenen, Novoderm, Varlane, Vaspit), or fluocortin 21-butylate, is a synthetic glucocorticoid corticosteroid which is marketed in Germany, Belgium, Luxembourg, Spain, and Italy.[1][2] Chemically, it is the butyl ester derivative of fluocortin.[1][2]

Fluocortin butyl
Clinical data
Trade namesLenen, Novoderm, Varlane, Vaspit
Other namesFCB; SHK-203; Fluocortin 21-butylate; Fluocortin butylate; Fluocortolone-21-carboxylate 21-butyl; 6α-Fluoro-11β-hydroxy-16α-methyl-3,20-dioxopregna-1,4-dien-21-oic acid butyl ester
Drug classCorticosteroid; Glucocorticoid
Identifiers
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
CompTox Dashboard (EPA)
ECHA InfoCard100.050.476
Chemical and physical data
FormulaC26H35FO5
Molar mass446.559 g·mol−1
3D model (JSmol)

It was patented in 1971 and approved for medical use in 1977.[3]

References

  1. Elks J (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. pp. 563–. ISBN 978-1-4757-2085-3.
  2. Index Nominum 2000: International Drug Directory. Taylor & Francis. 2000. pp. 457–. ISBN 978-3-88763-075-1.
  3. Fischer J, Ganellin CR (2006). Analogue-based Drug Discovery. John Wiley & Sons. p. 487. ISBN 9783527607495.


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