Pregnenolone 16α-carbonitrile

Pregnenolone 16α-carbonitrile (PCN) is a synthetic, steroidal antiglucocorticoid and pregnane X receptor agonist.[1][2][3]

Pregnenolone 16α-carbonitrile
Names
IUPAC name
(3S,8S,9S,10R,13S,14S,16R,17S)-17-acetyl-3-hydroxy-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-16-carbonitrile
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
Properties
C22H31NO2
Molar mass 341.49 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

See also

References

  1. J.I. Mason (2 September 2003). Genetics of Steroid Biosynthesis and Function. CRC Press. pp. 449–. ISBN 978-0-203-30149-4.
  2. Giacinto Bagetta; Marco Cosentino; Marie Tiziana Corasaniti; Shinobu Sakurada (19 April 2016). Herbal Medicines: Development and Validation of Plant-derived Medicines for Human Health. CRC Press. pp. 250–. ISBN 978-1-4398-3769-6.
  3. Larisa Y. Poluektova; J. Victor Garcia-Martinez; Yoshio Koyanagi; Markus G. Manz; Andrew M. Tager (18 February 2015). Humanized Mice for HIV Research. Springer. pp. 350–. ISBN 978-1-4939-1655-9.


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