Isopropamide

Isopropamide (R5) is a long-acting anticholinergic drug. It is used in the treatment of peptic ulcers and other gastrointestinal disorders involving hyperacidity (gastrointestinal acidosis) and hypermotility. Chemically, it contains a quaternary ammonium group. It is most often provided as an iodide salt, but is also available as a bromide or chloride salt. It was discovered at Janssen Pharmaceutica in 1954.

Isopropamide
Clinical data
MedlinePlusa694006
Routes of
administration
Oral
ATC code
Legal status
Legal status
  • US: ℞-only and Unscheduled
  • In general: unscheduled
Identifiers
CAS Number
PubChem CID
DrugBank
ChemSpider
UNII
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.028.470
Chemical and physical data
FormulaC23H33N2O+
Molar mass353.530 g·mol−1
3D model (JSmol)
 NY (what is this?)  (verify)

References

    Further reading

    • Seeherman R (October 1957). "Isopropamide iodide: a long-acting anticholinergic". Delaware Medical Journal. 29 (10): 265–9. PMID 13473394.
    • Boss Jr EG, Buchanan GC (November 1957). "Effect of isopropamide iodide on basal gastric secretion in the human". Gastroenterology. 33 (5): 730–6. PMID 13480414.
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