Tridihexethyl

Tridihexethyl
Clinical data
ATC code	A03AB08 (WHO) ;
Identifiers
	IUPAC name 3-cyclohexyl-N,N,N-triethyl-3-hydroxy-3-phenylpropan-1-aminium;
CAS Number	60-49-1 ;
PubChem CID	20299;
DrugBank	DB00505 ;
ChemSpider	19124 ;
UNII	7HE50A367X;
ChEBI	CHEBI:9701 ;
ChEMBL	ChEMBL1201354 ;
CompTox Dashboard (EPA)	DTXSID0048553 ;
Chemical and physical data
Formula	C21H36NO+
Molar mass	318.525 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES OC(c1ccccc1)(CC[N+](CC)(CC)CC)C2CCCCC2;
	InChI InChI=1S/C21H36NO/c1-4-22(5-2,6-3)18-17-21(23,19-13-9-7-10-14-19)20-15-11-8-12-16-20/h7,9-10,13-14,20,23H,4-6,8,11-12,15-18H2,1-3H3/q+1 ; Key:NPRHVSBSZMAEIN-UHFFFAOYSA-N ;
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Tridihexethyl (which is commonly used as its chloride salt, tridihexethyl chloride) is an anticholinergic, antimuscarinic and antispasmodic drug. It may be used, usually in combination with other drugs, to treat acquired nystagmus[1] or peptic ulcer disease.[2] Many patients discontinue the drug because of unwanted side effects.

It is also known as Pathilon or Propethonum. [3]

References

Leigh RJ, Burnstine TH, Ruff RL, Kasmer RJ (November 1991). "Effect of anticholinergic agents upon acquired nystagmus: a double-blind study of trihexyphenidyl and tridihexethyl chloride". Neurology. 41 (11): 1737–41. doi:10.1212/wnl.41.11.1737. PMID 1944902. S2CID 23270800.
"DB00505 (Tridihexethyl)". DrugBank.
"Tridihexethyl". Mongabay.com. Archived from the original on 2007-11-15.

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[pmid1944902-1] Leigh RJ, Burnstine TH, Ruff RL, Kasmer RJ (November 1991). "Effect of anticholinergic agents upon acquired nystagmus: a double-blind study of trihexyphenidyl and tridihexethyl chloride". Neurology. 41 (11): 1737–41. doi:10.1212/wnl.41.11.1737. PMID 1944902. S2CID 23270800.

[2] "DB00505 (Tridihexethyl)". DrugBank.

[3] "Tridihexethyl". Mongabay.com. Archived from the original on 2007-11-15.