Segesterone

Segesterone (INN, USAN),[1][2] also known as 17α-hydroxy-16-methylene-19-norprogesterone or as 17α-deacetylnestorone, is a steroidal progestin of the 19-norprogesterone group that was never marketed.[3] An acetate ester, segesterone acetate, better known as nestorone or elcometrine, is marketed for clinical use.[4] Segesterone acetate produces segesterone as a metabolite.[5]

This article is about a non-clinically used progestin compound. For the pharmaceutical drug, see segesterone acetate.
Segesterone
Clinical data
Other names17α-Hydroxy-16-methylene-19-norprogesterone; 16-Methylene-17α-hydroxy-19-norpregn-4-ene-3,20-dione; 17α-Deacetylnestorone
Identifiers
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC21H28O3
Molar mass328.452 g·mol−1
3D model (JSmol)

References
  1. https://www.who.int/medicines/publications/druginformation/innlists/PL89.pdf
  2. http://chem.sis.nlm.nih.gov/chemidplus/rn/7690-08-6
  3. https://pubchem.ncbi.nlm.nih.gov/compound/11823650
  4. Thomas L. Lemke; David A. Williams (24 January 2012). Foye's Principles of Medicinal Chemistry. Lippincott Williams & Wilkins. pp. 1403–. ISBN 978-1-60913-345-0.
  5. Prasad PV, Bashir M, Sitruk-Ware R, Kumar N (2010). "Single-dose pharmacokinetics of Nestorone, a potential female-contraceptive". Steroids. 75 (3): 252–64. doi:10.1016/j.steroids.2009.12.011. PMID 20064539. S2CID 205253216.



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