BHFF

BHFF is a compound used in scientific research which acts as a positive allosteric modulator at the GABAB receptor. It has anxiolytic effects in animal studies, and good oral bioavailability.[1]

BHFF
Identifiers
CAS Number
PubChem CID
ChemSpider
CompTox Dashboard (EPA)
ECHA InfoCard100.229.838
Chemical and physical data
FormulaC17H21F3O3
Molar mass330.347 g·mol−1
3D model (JSmol)
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References

  1. Malherbe P, Masciadri R, Norcross RD, Knoflach F, Kratzeisen C, Zenner MT, et al. (June 2008). "Characterization of (R,S)-5,7-di-tert-butyl-3-hydroxy-3-trifluoromethyl-3H-benzofuran-2-one as a positive allosteric modulator of GABAB receptors". British Journal of Pharmacology. 154 (4): 797–811. doi:10.1038/bjp.2008.135. PMC 2439845. PMID 18536733.
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