Butofilolol

Butofilolol
Clinical data
Other names	CM-6805
ATC code	none;
Identifiers
	IUPAC name (RS)-1-[2-[3-(tert-butylamino)-2-hydroxypropoxy]-5-fluorophenyl]butan-1-one;
CAS Number	58930-32-8 ;
PubChem CID	68838;
ChemSpider	62071 ;
UNII	4AZC6Y5A8G;
ChEMBL	ChEMBL157443 ;
ECHA InfoCard	100.055.892
Chemical and physical data
Formula	C17H26FNO3
Molar mass	311.397 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES Fc1ccc(OCC(O)CNC(C)(C)C)c(c1)C(=O)CCC;
	InChI InChI=1S/C17H26FNO3/c1-5-6-15(21)14-9-12(18)7-8-16(14)22-11-13(20)10-19-17(2,3)4/h7-9,13,19-20H,5-6,10-11H2,1-4H3 ; Key:NMBNQRJDEPOXCP-UHFFFAOYSA-N ;
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Butofilolol (trade name Cafide) is a beta-blocker drug for the treatment of essential hypertension (high blood pressure).[1][2] It is not known to be marketed anywhere.

References

Houin G, Barre J, Jeanniot JP, Ledudal P, Cautreels W, Tillement JP (1984). "Pharmacokinetics of butofilolol (CAFIDE) after repeated oral administration in man". International Journal of Clinical Pharmacology Research. 4 (3): 175–83. PMID 6149195.
Toussain P, Gay G, Debry G (June 1983). "[Long-term hypotensive treatment by butofilolol]". Annales de Cardiologie et d'Angeiologie. 32 (4): 277–83. PMID 6412614.

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[1] Houin G, Barre J, Jeanniot JP, Ledudal P, Cautreels W, Tillement JP (1984). "Pharmacokinetics of butofilolol (CAFIDE) after repeated oral administration in man". International Journal of Clinical Pharmacology Research. 4 (3): 175–83. PMID 6149195.

[2] Toussain P, Gay G, Debry G (June 1983). "[Long-term hypotensive treatment by butofilolol]". Annales de Cardiologie et d'Angeiologie. 32 (4): 277–83. PMID 6412614.