Exaprolol
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Names | |
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IUPAC name
1-(2-Cyclohexylphenoxy)-3-(propan-2-ylamino)propan-2-ol | |
Other names
Esprolol | |
Identifiers | |
3D model (JSmol) |
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KEGG | |
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Properties | |
C18H29NO2 | |
Molar mass | 291.435 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
Infobox references | |
Exaprolol is a beta-adrenoceptor antagonist.[1]
Synthesis
![](../I/Exaprolol_synthesis.svg.png.webp)
Exaprolol synthesis[2]
References
- Van Waarde, A; Doorduin, J; De Jong, JR; Dierckx, RA; Elsinga, PH (2008). "Synthesis and preliminary evaluation of (S)-11C-exaprolol, a novel beta-adrenoceptor ligand for PET". Neurochemistry International. 52 (4–5): 729–33. doi:10.1016/j.neuint.2007.09.009. PMID 17961850.
- Carissimi, M; Gentili, P; Grumelli, E; Milla, E; Picciola, G; Ravenna, F (1976). "Basic ethers of cyclohexylphenols with beta-blocking activity: Synthesis and pharmacological study of exaprolol". Arzneimittel-Forschung. 26 (4): 506–16. PMID 8056.
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