Uldazepam
Uldazepam is a drug which is a benzodiazepine derivative.[1] It has sedative and anxiolytic effects similar to those of other benzodiazepines.[2][3]
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| Other names | 7-chloro-5-(2-chlorophenyl)-N-prop-2-enoxy-3H-1,4-benzodiazepin-2-amine |
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| Formula | C18H15Cl2N3O |
| Molar mass | 360.24 g·mol−1 |
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Synthesis
Thio thionamide is even more prone to amidine formation than the lactam itself.
Uldazepam synthesis: J. B. Hester, Jr., DE 2005176 (1970); Chem. Abstr., 73: 99,001t (1970).
Reaction of thionamide (2) with O-allyl-hydroxylamine gave the oximino (3) uldazepam.
See also
References
- "Uldazepam U 31920". Psychotropics. Retrieved 12 June 2013.
- Oelschläger H, Ellaithy MM, Volke J (February 1988). "[Mechanism of the polarographic reduction of the tranquilizer uldazepam]". Archiv der Pharmazie (in German). 321 (2): 69–72. doi:10.1002/ardp.19883210205. PMID 3369929. S2CID 96356746.
- Itil TM, Akpinar S, Ozkut H, Balki N, Herrmann WM (June 1974). "Clinical and computerized EEG effects of U-31,920, a new anxiolytic". Current Therapeutic Research, Clinical and Experimental. 16 (6): 642–54. PMID 4211146.
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