Menthyl isovalerate
Menthyl isovalerate, also known as validolum, is the menthyl ester of isovaleric acid. It is a transparent oily, colorless liquid with a smell of menthol. It is very slightly soluble in ethanol, while practically insoluble in water. It is used as a food additive for flavor and fragrance.[1]
Names | |
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IUPAC name
(1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl 3-methylbutanoate | |
Other names
Validolum; Valofin; Validol; Menthoval | |
Identifiers | |
3D model (JSmol) |
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ChemSpider | |
ECHA InfoCard | 100.036.766 |
PubChem CID |
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UNII | |
CompTox Dashboard (EPA) |
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Properties | |
C15H28O2 | |
Molar mass | 240.387 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
Infobox references | |
Medical use
In Poland, Bulgaria, and the former Soviet Union states including Russia, menthyl isovalerate is sold as an anxiolytic under various trade names including Validol, Valofin, and Menthoval.[2][3][4]
See also
References
- Menthyl isovalerate
- Russian Medications List and Possible Side Effects
- "Farmak Product Information - Validol" (PDF). Archived from the original (PDF) on 2016-03-15. Retrieved 2013-04-05.
- Bondarenko IP, Liashenko MM, Chirkov SN, Ermakovich II (1996). "A comparative evaluation of the antianginal action of commercially and noncommercially produced validol in neurocirculatory dystonia and stenocardia". Lik Sprava. Mar–Apr (3–4): 110–113. PMID 9035841.
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