Androstane

Androstane is a C19 steroid with a gonane core. Androstane can exist as either of two isomers, known as 5α-androstane and 5β-androstane.

Androstane
Names
IUPAC name
(8S,9S,10S,13S,14S)-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene
Other names
Etioallocholane; 10β,13β-Dimethylgonane
Identifiers
3D model (JSmol)
ChEBI
ChemSpider
Properties
C19H32
Molar mass 260.465 g·mol−1
Density 0.95 g/ml
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

Pharmacology

5α-Androstane is reported to be effective as an androgen, in spite of having no oxygen substitutions.[1][2]

See also

References

  1. Wilson JD (1996). "Role of dihydrotestosterone in androgen action". Prostate Suppl. 6: 88–92. doi:10.1002/(SICI)1097-0045(1996)6+<88::AID-PROS17>3.0.CO;2-N. PMID 8630237.
  2. Segaloff A, Gabbard RB (1960). "5α-Androstane—An Androgenic Hydrocarbon". Endocrinology. 67 (6): 887–889. doi:10.1210/endo-67-6-887. ISSN 0013-7227. PMID 13749674.


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