CDK12

CDK12 cyclin-dependent kinase 12 is a protein kinase that in humans is encoded by the CDK12 gene.[5][6][7] This enzyme is a member of cyclin-dependent kinase protein family.

CDK12
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesCDK12, CRK7, CRKR, CRKRS, cyclin-dependent kinase 12, cyclin dependent kinase 12
External IDsOMIM: 615514 MGI: 1098802 HomoloGene: 128632 GeneCards: CDK12
Gene location (Human)
Chr.Chromosome 17 (human)[1]
Band17q12Start39,461,486 bp[1]
End39,564,907 bp[1]
RNA expression pattern


More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

51755

69131

Ensembl

ENSG00000167258

ENSMUSG00000003119

UniProt

Q9NYV4

Q14AX6

RefSeq (mRNA)

NM_015083
NM_016507

NM_001109626
NM_001109628
NM_026952

RefSeq (protein)

NP_055898
NP_057591

NP_001103096
NP_001103098
NP_081228

Location (UCSC)Chr 17: 39.46 – 39.56 MbChr 11: 98.2 – 98.28 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

References

  1. GRCh38: Ensembl release 89: ENSG00000167258 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000003119 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Nagase T, Ishikawa K, Suyama M, Kikuno R, Hirosawa M, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (May 1999). "Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 5 (6): 355–64. doi:10.1093/dnares/5.6.355. PMID 10048485.
  6. Ko TK, Kelly E, Pines J (Oct 2001). "CrkRS: a novel conserved Cdc2-related protein kinase that colocalises with SC35 speckles". J Cell Sci. 114 (Pt 14): 2591–603. PMID 11683387.
  7. "Entrez Gene: CDK12 cyclin-dependent kinase 12".

Further reading


This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.