DCLK1

Serine/threonine-protein kinase DCLK1 is an enzyme that in humans is encoded by the DCLK1 gene.[5][6][7]

DCLK1
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesDCLK1, CL1, CLICK1, DCAMKL1, DCDC3A, DCLK, doublecortin like kinase 1
External IDsOMIM: 604742 MGI: 1330861 HomoloGene: 130530 GeneCards: DCLK1
Gene location (Human)
Chr.Chromosome 13 (human)[1]
Band13q13.3Start35,768,652 bp[1]
End36,131,306 bp[1]
RNA expression pattern


More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

9201

13175

Ensembl

ENSG00000133083

ENSMUSG00000027797

UniProt

O15075

Q9JLM8

RefSeq (mRNA)
RefSeq (protein)
Location (UCSC)Chr 13: 35.77 – 36.13 MbChr 3: 55.24 – 55.54 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

DCLK1 is a marker for tuft cells.

References

  1. GRCh38: Ensembl release 89: ENSG00000133083 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000027797 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Omori Y, Suzuki M, Ozaki K, Harada Y, Nakamura Y, Takahashi E, Fujiwara T (Oct 1998). "Expression and chromosomal localization of KIAA0369, a putative kinase structurally related to Doublecortin". J Hum Genet. 43 (3): 169–77. doi:10.1007/s100380050063. PMID 9747029.
  6. Sossey-Alaoui K, Srivastava AK (May 1999). "DCAMKL1, a brain-specific transmembrane protein on 13q12.3 that is similar to doublecortin (DCX)". Genomics. 56 (1): 121–6. doi:10.1006/geno.1998.5718. PMID 10036192.
  7. "Entrez Gene: DCAMKL1 doublecortin and CaM kinase-like 1".

Further reading

  • Overview of all the structural information available in the PDB for UniProt: O15075 (Serine/threonine-protein kinase DCLK1) at the PDBe-KB.


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