List of naturally occurring phenethylamines

Naturally occurring phenethylamines are organic compounds which may be thought of as being derived from phenethylamine itself that are found in living organisms.

San Pedro cactus contain several phenethylamines.

Tyramine is a phenethylamine that occurs widely in plants[1] and animals, and is metabolized by various enzymes, including monoamine oxidases. Substituted phenethylamines like mescaline and lophophine are found in psychoactive cactus.

List of phenethylamines

Selected phenethylamines
Short Name Origin Rα R4 R5 RN1 RN2 Full Name
PhenethylamineNatural‹See Tfd›?‹See Tfd›?‹See Tfd›?‹See Tfd›?‹See Tfd›?2-phenylethan-1-amine
HordenineNatural‹See Tfd›?‹See Tfd›?‹See Tfd›?‹See Tfd›?‹See Tfd›?N,N-Dimethyltyramine
LophophineNatural‹See Tfd›?‹See Tfd›?‹See Tfd›?‹See Tfd›?‹See Tfd›?3-methoxy-4,5-methylenedioxyphenethylamine
MescalineNatural‹See Tfd›?‹See Tfd›?‹See Tfd›?‹See Tfd›?‹See Tfd›?3,4,5-trimethoxyphenethylamine
DMPEANatural‹See Tfd›?‹See Tfd›?‹See Tfd›?‹See Tfd›?‹See Tfd›?3,4-dimethoxyphenethylamine
TyramineNatural‹See Tfd›?‹See Tfd›?‹See Tfd›?‹See Tfd›?‹See Tfd›?
Natural‹See Tfd›?‹See Tfd›?‹See Tfd›?‹See Tfd›?‹See Tfd›?3-hydroxy-4,5-dimethoxyphenethylamine
3-MTNatural‹See Tfd›?‹See Tfd›?‹See Tfd›?‹See Tfd›?‹See Tfd›?4-hydroxy-3-methoxyphenethylamine
Natural‹See Tfd›?‹See Tfd›?‹See Tfd›?‹See Tfd›?‹See Tfd›?4-hydroxy-3,5-dimethoxyphenethylamine

References

  1. T. A. Smith (1977) Phytochemistry 16 9-18.
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