NBUMP
NBUMP is a highly selective 5-HT1A receptor partial agonist (Ki = 0.1 nM; IA = 40%) with an arylpiperazine structure.[1] It is one of the highest affinity ligands for the 5-HT1A receptor known.[1] It displays 460- and 260-fold selectivity for 5-HT1A over the α1-adrenergic and D2 receptors, respectively.[1]
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| Formula | C26H39N3O2 |
| Molar mass | 425.617 g·mol−1 |
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See also
References
- Glennon RA (2006). "Strategies for the development of selective serotonergic agents". In Roth BL (ed.). The Serotonin Receptors: From Molecular Pharmacology to Human Therapeutics (The Receptors). Totowa, NJ: Humana Press. p. 113. ISBN 1-58829-568-0.
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