Chlorphenoxamine
Chlorphenoxamine (Phenoxene) is an antihistamine and anticholinergic used as an antipruritic[1] and antiparkinsonian[2] agent. It is an analog of diphenhydramine.[3]
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Routes of administration | Oral, topical |
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Pharmacokinetic data | |
Bioavailability | Well absorbed |
Metabolism | Likely hepatic |
Excretion | Renal |
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ECHA InfoCard | 100.115.538 ![]() |
Chemical and physical data | |
Formula | C18H22ClNO |
Molar mass | 303.83 g·mol−1 |
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References
- Bazex A, Dupre A, Christol B (1963). "[Trial treatment of urticaria with chlorphenoxamine]". Clinique. 58: 447–50. PMID 13967113.
- Uldall PR, Walton JN, Newell DJ (June 1961). "Chlorphenoxamine hydrochloride in parkinsonism. A controlled trial". British Medical Journal. 1 (5240): 1649–52. doi:10.1136/bmj.1.5240.1649. PMC 1954253. PMID 13779077.
- Arnold H, Brock N, Kuhas E, Lorenz D (January 1954). "Beitrag Zur Wirkung Von Antihistamin-Substanzen. 1. Chemische Konstitution Und Pharmakologische Wirkung in Der Gruppe Der Basischen Benzhydrylaether" [Contribution to the Effect Of Antihistamine Substances. 1. Chemical constitution and pharmacological activity in the group of basic benzhydrylethers]. Arzneimittel-Forschung [Drug Research] (in German). 4 (3): 189–94. PMID 13159698.
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For topical use |
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See also: Receptor/signaling modulators • Monoamine metabolism modulators • Monoamine reuptake inhibitors |
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