TAAR3

Putative trace amine-associated receptor 3 (TAAR3) is a human pseudogene with the gene symbol TAAR3P.[2][3][4][5] In other species such as mice, TAAR3 is a functional protein-coding gene that encodes a trace amine-associated receptor protein.

TAAR3P
Identifiers
AliasesTAAR3P, GPR57, GPR58, TAAR2, TAAR3, trace amine associated receptor 3 (gene/pseudogene), trace amine associated receptor 3, pseudogene
External IDsGeneCards: TAAR3P
Orthologs
SpeciesHumanMouse
Entrez

9288

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Ensembl

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UniProt

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RefSeq (mRNA)

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RefSeq (protein)

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Location (UCSC)n/an/a
PubMed search[1]n/a
Wikidata
View/Edit Human

Ligands: Isobutylamine is a known ligand of TAAR3 in mice associated with sexual behaviour in male mice.[6]

Isopentylamine was identified as a ligand for murine TAAR3 eliciting aversive behavior.[7]

See also

References
  1. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  2. HGNC:4513 Retrieved 28 November 2019
  3. Lee DK, Lynch KR, Nguyen T, Im DS, Cheng R, Saldivia VR, et al. (February 2000). "Cloning and characterization of additional members of the G protein-coupled receptor family". Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression. 1490 (3): 311–23. doi:10.1016/s0167-4781(99)00241-9. PMID 10684976.
  4. Lindemann L, Ebeling M, Kratochwil NA, Bunzow JR, Grandy DK, Hoener MC (March 2005). "Trace amine-associated receptors form structurally and functionally distinct subfamilies of novel G protein-coupled receptors". Genomics. 85 (3): 372–85. doi:10.1016/j.ygeno.2004.11.010. PMID 15718104.
  5. "Entrez Gene: TAAR3 trace amine associated receptor 3".
  6. Harmeier A, Meyer CA, Staempfli A, Casagrande F, Petrinovic MM, Zhang YP, et al. (2018). "How Female Mice Attract Males: A Urinary Volatile Amine Activates a Trace Amine-Associated Receptor That Induces Male Sexual Interest". Frontiers in Pharmacology. 9: 924. doi:10.3389/fphar.2018.00924. PMC 6104183. PMID 30158871.
  7. Liberles SD (October 2015). "Trace amine-associated receptors: ligands, neural circuits, and behaviors". Current Opinion in Neurobiology. 34: 1–7. doi:10.1016/j.conb.2015.01.001. PMC 4508243. PMID 25616211.
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