P2RY10

Putative P2Y purinoceptor 10 is a protein that, in humans, is encoded by the P2RY10 gene.[5][6][7]

P2RY10
Identifiers
AliasesP2RY10, LYPSR2, P2Y10, purinergic receptor P2Y10, P2Y receptor family member 10
External IDsOMIM: 300529 MGI: 1926076 HomoloGene: 8717 GeneCards: P2RY10
Gene location (Human)
Chr.X chromosome (human)[1]
BandXq21.1Start78,945,332 bp[1]
End78,963,727 bp[1]
RNA expression pattern
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

27334

78826

Ensembl

ENSG00000078589

ENSMUSG00000050921

UniProt

O00398

Q8BFU7

RefSeq (mRNA)

NM_014499
NM_198333
NM_001324218
NM_001324221
NM_001324225

NM_172435
NM_001357810

RefSeq (protein)

NP_001311147
NP_001311150
NP_001311154
NP_055314
NP_938147

NP_766023
NP_001344739

Location (UCSC)Chr X: 78.95 – 78.96 MbChr X: 107.09 – 107.1 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Function

The protein encoded by this gene belongs to the family of G-protein coupled receptors that is preferentially activated by adenosine and uridine nucleotides. Two alternatively spliced transcript variants encoding the same protein isoform have been found for this gene.[7]

See also

References

  1. GRCh38: Ensembl release 89: ENSG00000078589 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000050921 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Adrian K, Bernhard MK, Breitinger HG, Ogilvie A (June 2000). "Expression of purinergic receptors (ionotropic P2X1-7 and metabotropic P2Y1-11) during myeloid differentiation of HL60 cells". Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression. 1492 (1): 127–38. doi:10.1016/S0167-4781(00)00094-4. PMID 11004484.
  6. Ralevic V, Burnstock G (September 1998). "Receptors for purines and pyrimidines". Pharmacological Reviews. 50 (3): 413–92. PMID 9755289.
  7. "Entrez Gene: P2RY10 purinergic receptor P2Y, G-protein coupled, 10".

Further reading

  • Berchtold S, Ogilvie AL, Bogdan C, Mühl-Zürbes P, Ogilvie A, Schuler G, Steinkasserer A (September 1999). "Human monocyte derived dendritic cells express functional P2X and P2Y receptors as well as ecto-nucleotidases". FEBS Letters. 458 (3): 424–8. doi:10.1016/S0014-5793(99)01197-7. PMID 10570953. S2CID 35306561.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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