OPN1SW

OPN1SW
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1KPN
Identifiers
Aliases	OPN1SW, BCP, BOP, CBT, opsin 1 (cone pigments), short-wave-sensitive, opsin 1, short wave sensitive
External IDs	OMIM: 613522 MGI: 99438 HomoloGene: 1291 GeneCards: OPN1SW
Gene location (Human)
Chr.	Chromosome 7 (human)[1]
End	128,775,790 bp[1]
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)[2]
End	29,388,468 bp[2]
RNA expression pattern
	More reference expression data
Gene ontology
Molecular function	• G-protein coupled receptor activity; • photoreceptor activity; • signal transducer activity; • G-protein coupled photoreceptor activity; • signaling receptor activity;
Cellular component	• integral component of membrane; • integral component of plasma membrane; • membrane; • photoreceptor outer segment; • photoreceptor disc membrane;
Biological process	• response to stimulus; • protein-chromophore linkage; • signal transduction; • visual perception; • retinoid metabolic process; • phototransduction; • detection of visible light; • G-protein coupled receptor signaling pathway; • cellular response to light stimulus;
	Sources:Amigo / QuickGO
Orthologs
	611
	12057
	ENSG00000128617
	ENSMUSG00000058831
	P03999
	P51491
	NM_001708
	NM_007538
	NP_001699
	NP_031564
	Wikidata
View/Edit Human	View/Edit Mouse

Blue-sensitive opsin is a protein that in humans is encoded by the OPN1SW gene.[5][6][7]

References

GRCh38: Ensembl release 89: ENSG00000128617 - Ensembl, May 2017
GRCm38: Ensembl release 89: ENSMUSG00000058831 - Ensembl, May 2017
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
Nathans J, Thomas D, Hogness DS (Apr 1986). "Molecular genetics of human color vision: the genes encoding blue, green, and red pigments". Science. 232 (4747): 193–202. CiteSeerX 10.1.1.461.5915. doi:10.1126/science.2937147. PMID 2937147.
Fitzgibbon J, Appukuttan B, Gayther S, Wells D, Delhanty J, Hunt DM (Feb 1994). "Localisation of the human blue cone pigment gene to chromosome band 7q31.3-32". Hum Genet. 93 (1): 79–80. doi:10.1007/bf00218919. PMID 8270261. S2CID 43548690.
"Entrez Gene: OPN1SW opsin 1 (cone pigments), short-wave-sensitive (color blindness, tritan)".

Applebury ML, Hargrave PA (1987). "Molecular biology of the visual pigments". Vision Res. 26 (12): 1881–95. doi:10.1016/0042-6989(86)90115-X. PMID 3303660. S2CID 34038855.
Swanson WH, Cohen JM (2003). "Color vision". Ophthalmology Clinics of North America. 16 (2): 179–203. doi:10.1016/S0896-1549(03)00004-X. PMID 12809157.
Weitz CJ, Went LN, Nathans J (1992). "Human tritanopia associated with a third amino acid substitution in the blue-sensitive visual pigment". Am. J. Hum. Genet. 51 (2): 444–6. PMC 1682686. PMID 1386496.
Weitz CJ, Miyake Y, Shinzato K, et al. (1992). "Human tritanopia associated with two amino acid substitutions in the blue-sensitive opsin". Am. J. Hum. Genet. 50 (3): 498–507. PMC 1684278. PMID 1531728.
Oprian DD, Asenjo AB, Lee N, Pelletier SL (1992). "Design, chemical synthesis, and expression of genes for the three human color vision pigments". Biochemistry. 30 (48): 11367–72. doi:10.1021/bi00112a002. PMID 1742276.
Sarkar G, Sommer SS (1989). "Access to a messenger RNA sequence or its protein product is not limited by tissue or species specificity". Science. 244 (4902): 331–4. doi:10.1126/science.2565599. PMID 2565599.
Nathans J, Piantanida TP, Eddy RL, et al. (1986). "Molecular genetics of inherited variation in human color vision". Science. 232 (4747): 203–10. doi:10.1126/science.3485310. PMID 3485310.
Shimmin LC, Mai P, Li WH (1997). "Sequences and evolution of human and squirrel monkey blue opsin genes". J. Mol. Evol. 44 (4): 378–82. doi:10.1007/PL00006157. PMID 9089077. S2CID 6425474.
Scherer SW, Cheung J, MacDonald JR, et al. (2003). "Human Chromosome 7: DNA Sequence and Biology". Science. 300 (5620): 767–72. doi:10.1126/science.1083423. PMC 2882961. PMID 12690205.
Gunther KL, Neitz J, Neitz M (2006). "A novel mutation in the short-wavelength-sensitive cone pigment gene associated with a tritan color vision defect". Vis. Neurosci. 23 (3–4): 403–9. doi:10.1017/S0952523806233169. PMID 16961973.

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[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000128617 - Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000058831 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid2937147-5] Nathans J, Thomas D, Hogness DS (Apr 1986). "Molecular genetics of human color vision: the genes encoding blue, green, and red pigments". Science. 232 (4747): 193–202. CiteSeerX 10.1.1.461.5915. doi:10.1126/science.2937147. PMID 2937147.

[pmid8270261-6] Fitzgibbon J, Appukuttan B, Gayther S, Wells D, Delhanty J, Hunt DM (Feb 1994). "Localisation of the human blue cone pigment gene to chromosome band 7q31.3-32". Hum Genet. 93 (1): 79–80. doi:10.1007/bf00218919. PMID 8270261. S2CID 43548690.

[entrez-7] "Entrez Gene: OPN1SW opsin 1 (cone pigments), short-wave-sensitive (color blindness, tritan)".

OPN1SW

See also

References

Further reading