P2RY13

P2Y purinoceptor 13 is a protein that in humans is encoded by the P2RY13 gene.[5][6][7]

P2RY13
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesP2RY13, GPCR1, GPR86, GPR94, P2Y13, SP174, FKSG77, purinergic receptor P2Y13
External IDsOMIM: 606380 MGI: 1921441 HomoloGene: 12543 GeneCards: P2RY13
Gene location (Human)
Chr.Chromosome 3 (human)[1]
Band3q25.1Start151,326,312 bp[1]
End151,329,549 bp[1]
RNA expression pattern
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

53829

74191

Ensembl

ENSG00000181631

ENSMUSG00000036362

UniProt

Q9BPV8

Q9D8I2

RefSeq (mRNA)

NM_023914
NM_176894

NM_028808

RefSeq (protein)

NP_795713

NP_083084

Location (UCSC)Chr 3: 151.33 – 151.33 MbChr 3: 59.21 – 59.21 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

The product of this gene, P2Y13, belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is activated by ADP. Two transcript variants encoding the same protein have been identified for this gene.[7]

See also

References
  1. GRCh38: Ensembl release 89: ENSG00000181631 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000036362 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Wittenberger T, Schaller HC, Hellebrand S (Mar 2001). "An expressed sequence tag (EST) data mining strategy succeeding in the discovery of new G-protein coupled receptors". J Mol Biol. 307 (3): 799–813. doi:10.1006/jmbi.2001.4520. PMID 11273702.
  6. Lee DK, Nguyen T, Lynch KR, Cheng R, Vanti WB, Arkhitko O, Lewis T, Evans JF, George SR, O'Dowd BF (Sep 2001). "Discovery and mapping of ten novel G protein-coupled receptor genes". Gene. 275 (1): 83–91. doi:10.1016/S0378-1119(01)00651-5. PMID 11574155.
  7. "Entrez Gene: P2RY13 purinergic receptor P2Y, G-protein coupled, 13".

Further reading
  • "P2Y Receptors: P2Y13". IUPHAR Database of Receptors and Ion Channels. International Union of Basic and Clinical Pharmacology.

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