Zearalanone

Zearalanone (ZAN) is a semi-synthetic mycoestrogen that is a derivative of zearalenone (ZEN).[1] Zearalanone is extracted from medical herbs and edible herbs alone with other substance called aflatoxins in the same time by a specific immunoaffinity column. Zearalanone has six analog. They are ZEN, zearalanone, α-zeralanol, β-zeralanol, α-zearalenol, and β-zearalenol.[2]

Zearalanone
Names
IUPAC name
(3S)-14,16-Dihydroxy-3-methyl-3,4,5,6,9,10,11,12-octahydro-1H-2-benzoxacyclotetradecine-1,7(8H)-dione monohydrate
Other names
Mycotoxin, ZAN
Identifiers
3D model (JSmol)
ChEBI
ChEMBL
ChemSpider
ECHA InfoCard 100.165.079
KEGG
UNII
Properties
C18H24O5
Molar mass 320.385 g·mol−1
Hazards
GHS pictograms
GHS Signal word Warning
H302, H312, H315, H319, H332, H335, H351
P201, P202, P261, P264, P270, P271, P280, P281, P301+312, P302+352, P304+312, P304+340, P305+351+338, P308+313, P312, P321, P322, P330, P332+313, P337+313, P362, P363, P403+233, P405, P501
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

See also

References

  1. Drzymala; et al. (April 28, 2012). "(3S)-14,16-Dihydroxy-3-methyl-3,4,5,6,9,10,11,12-octahydro-1H-2-benzoxacyclotetradecine-1,7(8H)-dione (zearalanone) monohydrate". Acta Crystallogr E. 68 (5): o1577. doi:10.1107/S1600536812018168. PMC 3344672. PMID 22590434.
  2. Sun, Shujuan (August 2018). "Determination of aflatoxin and zearalenone analogs in edible and medicinal herbs using a group-specific immunoaffinity column coupled to ultra-high-performance liquid chromatography with tandem mass spectrometry". Journal of Chromatography B. 1092: 228–236. doi:10.1016/j.jchromb.2018.06.012. PMID 29909149.


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