2-Fluorodeschloroketamine

2-Fluorodeschloroketamine (also known as 2'-Fl-2-Oxo-PCM, Fluoroketamine and 2-FDCK) is a dissociative anesthetic[1] that has been sold online as a designer drug.[2][3][4] It is an analogue of ketamine where the chlorine group has been replaced by fluorine.

2-Fluorodeschloroketamine
Legal status
Legal status
  • CA: Schedule I
  • UK: Class B
  • Illegal in Italy, Japan, Latvia, Singapore, Sweden and Switzerland
Identifiers
CAS Number
PubChem CID
ChemSpider
UNII
Chemical and physical data
FormulaC13H16FNO
Molar mass221.275 g·mol−1
3D model (JSmol)

2-Fluorodeschloroketamine is illegal in Italy,[5] Japan,[6] Latvia,[7] Singapore,[8] Sweden,[9] Switzerland,[10] as well as being covered by blanket bans in Canada and the UK.

See also

References
  1. Moghimi A, Rahmani S, Zare R, Sadeghzadeh M (July 18, 2014). "Synthesis of 2-(2-Fluorophenyl)-2-methylamino-Cyclohexanone as a New Ketamine Derivative". Synthetic Communications. 44 (14): 2021–2028. doi:10.1080/00397911.2014.885053. ISSN 0039-7911.
  2. Davidsen AB, Mardal M, Holm NB, Andreasen AK, Johansen SS, Noble C, et al. (February 2020). "Ketamine analogues: Comparative toxicokinetic in vitro-in vivo extrapolation and quantification of 2-fluorodeschloroketamine in forensic blood and hair samples". Journal of Pharmaceutical and Biomedical Analysis. 180: 113049. doi:10.1016/j.jpba.2019.113049. PMID 31881397.
  3. Wang PF, Neiner A, Lane TR, Zorn KM, Ekins S, Kharasch ED (February 2019). "Halogen Substitution Influences Ketamine Metabolism by Cytochrome P450 2B6: In Vitro and Computational Approaches". Molecular Pharmaceutics. 16 (2): 898–906. doi:10.1021/acs.molpharmaceut.8b01214. PMID 30589555.
  4. Tang MH, Li TC, Lai CK, Chong YK, Ching CK, Mak TW (July 2020). "Emergence of new psychoactive substance 2-fluorodeschloroketamine: Toxicology and urinary analysis in a cluster of patients exposed to ketamine and multiple analogues". Forensic Science International. 312: 110327. doi:10.1016/j.forsciint.2020.110327. PMID 32460225.
  5. "Aggiornamento delle tabelle contenenti l'indicazione delle sostanze stupefacenti e psicotrope, di cui al decreto del Presidente della Repubblica 9 ottobre 1990, n. 309 e successive modificazioni ed integrazioni. Inserimento nella tabella I e nella tabella IV di nuove sostanze psicoattive". Article 1, Decree of March 13, 2020 (in Italian).
  6. "指定薬物一覧" (PDF) (in Japanese). Ministry of Health, Labour and Welfare.
  7. "Noteikumi par Latvijā kontrolējamajām narkotiskajām vielām, psihotropajām vielām un prekursoriem" (in Latvian). Latvijas Republikas tiesību akti.
  8. "Misuse of Drugs Act – Singapore Statutes Online". sso.agc.gov.sg.
  9. Riksdagsförvaltningen. "Förordning (1999:58) om förbud mot vissa hälsofarliga varor Svensk författningssamling 1999:1999:58 t.o.m. SFS 2019:631 – Riksdagen". www.riksdagen.se (in Swedish).
  10. "Verordnung des EDI über die Verzeichnisse der Betäubungsmittel, psychotropen Stoffe, Vorläuferstoffe und Hilfschemikalien" (in German). Der Bundesrat.
This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.