Bremazocine
Bremazocine is a κ-opioid receptor agonist related to pentazocine. It has potent and long-lasting analgesic and diuretic effects.[1] It has 200 times the activity of morphine, but appears to have no addictive properties and does not depress breathing.[2] The crystal structure of bremazocine was determined in 1984 [3]
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| Routes of administration | Oral |
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| Formula | C20H29NO2 |
| Molar mass | 315.457 g·mol−1 |
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See also
References
- Dortch-Carnes J, Potter DE (2005). "Bremazocine: a kappa-opioid agonist with potent analgesic and other pharmacologic properties". CNS Drug Reviews. 11 (2): 195–212. doi:10.1111/j.1527-3458.2005.tb00270.x. PMC 6741727. PMID 16007240.
- Patrick, Graham (2013). An Introduction to Medicinal Chemistry (5th expanded ed.). Oxford University Press. p. 641. ISBN 0199697396.
- Verlinde CL, Blaton NM, De Ranter CJ, Peeters OM (1984). "5-Ethyl-2'-hydroxy-2-[(1-hydroxycyclopropyl) methyl]-9, 9-dimethyl-6, 7-benzomorphan hydrochloride (bremazocine), C20H29NO2. HCl". Acta Crystallogr. C. 40: 1759–1761.
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See also: Receptor/signaling modulators • Signaling peptide/protein receptor modulators | |
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