Diethylstilbestrol dilaurate

Diethylstilbestrol dilaurate
Clinical data
Trade names	Acnestrol-Lotion
Identifiers
	IUPAC name 4-[(3E)-4-[4-(Dodecanoyloxy)phenyl]hex-3-en-3-yl]phenyl dodecanoate;
Chemical and physical data
Formula	C42H64O4
Molar mass	632.970 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CCCCCCCCCCCC(=O)OC1=CC=C(C=C1)C(\CC)=C(/CC)C1=CC=C(OC(=O)CCCCCCCCCCC)C=C1;
	InChI InChI=1S/C42H64O4/c1-5-9-11-13-15-17-19-21-23-25-41(43)45-37-31-27-35(28-32-37)39(7-3)40(8-4)36-29-33-38(34-30-36)46-42(44)26-24-22-20-18-16-14-12-10-6-2/h27-34H,5-26H2,1-4H3/b40-39+; Key:GEWSRLGHTICJOA-XQQUEIPISA-N;

Diethylstilbestrol dilaurate (brand name Acnestrol-Lotion) is a synthetic, nonsteroidal estrogen of the stilbestrol group and an ester of diethylstilbestrol (DES) that was previously marketed but is now no longer available.[1][2] It was formulated and used as a micronized topical medication to treat acne in adolescent boys and young men.[2][3] The drug was marketed as early as 1951.[4]

References

Elks J (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. p. 397. ISBN 978-1-4757-2085-3.
Canadian Pharmaceutical Association (1963). Compendium of pharmaceutical specialties (Canada) 1963. Canadian Pharmaceutical Association. p. 14.
Frank SB (1971). Acne Vulgaris. Thomas. p. 259.
New York State Journal of Medicine. Medical Society of the State of New York. April 1951. p. 1313.

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