Estradiol furoate
Estradiol furoate (EF), or estradiol 17β-furoate, sold under the brand name Di-Folliculine, is an estrogen medication and estrogen ester which is no longer marketed.[1] It is the C17β furoate ester of estradiol.[1] Estradiol benzoate has also been marketed under the brand name Di-Folliculine, and should not be confused with estradiol furoate.[2]
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| Trade names | Di-Folliculine |
| Other names | EF; 17-Furoylestradiol; 17-(2-Furancarbonyl)estradiol |
| Routes of administration | Intramuscular injection |
| Drug class | Estrogen; Estrogen ester |
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| Chemical and physical data | |
| Formula | C23H26O4 |
| Molar mass | 366.457 g·mol−1 |
| 3D model (JSmol) | |
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The duration of action of the related estradiol ester estradiol 3-furoate by intramuscular injection was studied in women in 1952.[3] Its duration in oil solution was found to be similar to that of estradiol benzoate in oil solution and shorter than that of estradiol dipropionate in oil solution.[3]
References
- Elks J (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. p. 898. ISBN 978-1-4757-2085-3.
- Pharmaceutical Abstracts. American Pharmaceutical Association. 1941. p. 149.
- Ferin J (January 1952). "Relative duration of action of natural and synthetic estrogens administered parenterally in women with estrogen deficiency". The Journal of Clinical Endocrinology and Metabolism. 12 (1): 28–35. doi:10.1210/jcem-12-1-28. PMID 14907837.
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