Hexestrol diphosphate

Hexestrol diphosphate (brand names Cytostatin, Cytostesin, Pharmestrin, Retalon Aquosum) is a synthetic, nonsteroidal estrogen of the stilbestrol group related to diethylstilbestrol and used as an estrogen and antineoplastic agent in the treatment of prostate cancer.[1][2][3] It is a water-soluble ester of hexestrol.[1] The medication has been known since at least 1956.[3]

Hexestrol diphosphate
Clinical data
Trade namesCytostatin, Cytostesin, Pharmestrin, Retalon Aquosum
Other namesDA-268; NSC-35752
Routes of
administration
Intravenous injection
Drug classEstrogen; Nonsteroidal estrogen
Identifiers
CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
Chemical and physical data
FormulaC18H24O8P2
Molar mass430.330 g·mol−1
3D model (JSmol)

See also

References

  1. Elks J (14 November 2014). "Chemical Data, Structures and Bibliographies". In Ganellin J, Elks J (eds.). The Dictionary of Drugs. Springer. p. 163. doi:10.1007/978-1-4757-2085-3. ISBN 978-1-4757-2085-3. OCLC 898564124.
  2. Milne GW (8 May 2018). Drugs: Synonyms and Properties: Synonyms and Properties. Taylor & Francis. pp. 1408–. ISBN 978-1-351-78989-9.
  3. Adami E, Marazzi-Uberti E (July–December 1956). "[Experimental research on prostatic antineoplastic agent: hexestrol diphosphate]". Giornale Italiano di Chemioterapia (in Italian). 3 (3–4): 362–9. ISSN 0017-0445. PMID 13462184.
This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.