GTF3C1

General transcription factor 3C polypeptide 1 is a protein that in humans is encoded by the GTF3C1 gene.[5][6][7]

GTF3C1
Identifiers
AliasesGTF3C1, TFIIIC, TFIIIC220, TFIIICalpha, general transcription factor IIIC subunit 1
External IDsOMIM: 603246 MGI: 107887 HomoloGene: 31040 GeneCards: GTF3C1
Gene location (Human)
Chr.Chromosome 16 (human)[1]
Band16p12.1Start27,459,555 bp[1]
End27,549,913 bp[1]
RNA expression pattern


More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

2975

233863

Ensembl

ENSG00000077235

ENSMUSG00000032777

UniProt

Q12789

Q8K284

RefSeq (mRNA)

NM_001286242
NM_001520

NM_207239

RefSeq (protein)

NP_001273171
NP_001511

NP_997122

Location (UCSC)Chr 16: 27.46 – 27.55 MbChr 7: 125.64 – 125.71 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Interactions

GTF3C1 has been shown to interact with GTF3C4.[8]

References

  1. GRCh38: Ensembl release 89: ENSG00000077235 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000032777 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Lagna G, Kovelman R, Sukegawa J, Roeder RG (May 1994). "Cloning and characterization of an evolutionarily divergent DNA-binding subunit of mammalian TFIIIC". Mol. Cell. Biol. 14 (5): 3053–64. doi:10.1128/mcb.14.5.3053. PMC 358673. PMID 8164661.
  6. L'Etoile ND, Fahnestock ML, Shen Y, Aebersold R, Berk AJ (Apr 1994). "Human transcription factor IIIC box B binding subunit". Proc. Natl. Acad. Sci. U.S.A. 91 (5): 1652–6. Bibcode:1994PNAS...91.1652L. doi:10.1073/pnas.91.5.1652. PMC 43221. PMID 8127861.
  7. "Entrez Gene: GTF3C1 general transcription factor IIIC, polypeptide 1, alpha 220kDa".
  8. Hsieh YJ, Kundu TK, Wang Z, Kovelman R, Roeder RG (Nov 1999). "The TFIIIC90 subunit of TFIIIC interacts with multiple components of the RNA polymerase III machinery and contains a histone-specific acetyltransferase activity". Mol. Cell. Biol. 19 (11): 7697–704. doi:10.1128/mcb.19.11.7697. PMC 84812. PMID 10523658.

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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