MEIS2

Homeobox protein Meis2 is a protein that in humans is encoded by the MEIS2 gene.[5][6]

MEIS2
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesMEIS2, HsT18361, MRG1, Meis homeobox 2, CPCMR
External IDsOMIM: 601740 MGI: 108564 HomoloGene: 7846 GeneCards: MEIS2
Gene location (Human)
Chr.Chromosome 15 (human)[1]
Band15q14Start36,889,204 bp[1]
End37,101,299 bp[1]
RNA expression pattern
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

4212

17536

Ensembl

ENSG00000134138

ENSMUSG00000027210

UniProt

O14770

P97367

RefSeq (mRNA)
RefSeq (protein)
Location (UCSC)Chr 15: 36.89 – 37.1 MbChr 2: 115.86 – 116.07 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

This gene encodes a homeobox protein belonging to the TALE ('three amino acid loop extension') family of homeodomain-containing proteins. TALE homeobox proteins are highly conserved transcription regulators, and several members have been shown to be essential contributors to developmental programs. Multiple transcript variants encoding distinct isoforms have been described for this gene.[6]

References

  1. GRCh38: Ensembl release 89: ENSG00000134138 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000027210 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Smith JE, Afonja O, Yee HT, Inghirami G, Takeshita K (Jan 1998). "Chromosomal mapping to 15q14 and expression analysis of the human MEIS2 homeobox gene". Mamm Genome. 8 (12): 951–2. doi:10.1007/s003359900621. PMID 9383298. S2CID 20187903.
  6. "Entrez Gene: MEIS2 Meis homeobox 2".

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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