TOX2
TOX high mobility group box family member 2, also known as TOX2, is a human gene.[1][2]
| TOX high mobility group box family member 2 | |||||||
|---|---|---|---|---|---|---|---|
| Identifiers | |||||||
| Symbol | TOX2 | ||||||
| Alt. symbols | C20orf100, GCX-1 | ||||||
| NCBI gene | 84969 | ||||||
| HGNC | 16095 | ||||||
| OMIM | 611163 | ||||||
| RefSeq | NM_001098796 | ||||||
| UniProt | Q96NM4 | ||||||
| Other data | |||||||
| Locus | Chr. 20 q13.12 | ||||||
| |||||||
The protein encoded by this gene is a member of a subfamily of transcription factors that also includes TOX, TOX3, and TOX4 that share almost identical HMG-box DNA-binding domains which function to modify chromatin structure.[3]
References
- "Entrez Gene: TOX high mobility group box family member 2".
- Kajitani T, Mizutani T, Yamada K, Yazawa T, Sekiguchi T, Yoshino M, Kawata H, Miyamoto K (May 2004). "Cloning and characterization of granulosa cell high-mobility group (HMG)-box protein-1, a novel HMG-box transcriptional regulator strongly expressed in rat ovarian granulosa cells". Endocrinology. 145 (5): 2307–18. doi:10.1210/en.2003-1343. PMID 14764631.
- O'Flaherty E, Kaye J (April 2003). "TOX defines a conserved subfamily of HMG-box proteins". BMC Genomics. 4 (1): 13. doi:10.1186/1471-2164-4-13. PMC 155677. PMID 12697058.
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