Ethinylestradiol/drospirenone

Ethinylestradiol/drospirenone (EE/DRSP), sold under the brand name Yasmin among others, is a combination of ethinylestradiol (EE), an estrogen, and drospirenone (DRSP), a progestin, antimineralocorticoid, and antiandrogen, which is used as a birth control pill to prevent pregnancy in women.[2][3][4][5] It is also indicated for the treatment of moderate acne, premenstrual syndrome (PMS), premenstrual dysphoric disorder (PMDD), and dysmenorrhea (painful menstruation) in women.[3] The medication is taken by mouth and contains 30 μg EE and 3 mg DRSP per tablet (brand names Yasmin, others) or 20 μg EE and 3 mg DRSP per tablet (brand names Yaz, Yasminelle, Nikki, others).[4][5] A formulation with levomefolic acid (vitamin B9) has also been marketed (brand names Beyaz, Safyral, others), with similar indications.[6][7] EE/DRSP is marketed widely throughout the world.[8]

Ethinylestradiol/drospirenone
Ethinylestradiol
Drospirenone
Combination of
EthinylestradiolEstrogen
DrospirenoneProgestogen; Progestin; Antimineralocorticoid; Antiandrogen
Clinical data
Trade namesWith 30 μg ethinylestradiol: Yasmin, others
With 20 μg ethinylestradiol: Yaz, Yasminelle, others
Other namesEE/DRSP
AHFS/Drugs.comProfessional Drug Facts
MedlinePlusa601050
License data
Pregnancy
category
Routes of
administration
By mouth
Drug classEstrogen; Progestin; Progestogen; Antimineralocorticoid; Antiandrogen
ATC code
Legal status
Legal status
Identifiers
KEGG

In 2017, it was the 98th most commonly prescribed medication in the United States, with more than eight million prescriptions.[9][10]

See also

References


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